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"HbA1C Misleading in Diabetic Patient with PNH"

"Objectives: We report a case of a patient with diabetes mellitus and unexpectedly low hemoglobin A1c results associated with paroxysmal nocturnal hemoglobinuria (PNH). We review the impact of shortened RBC half-life on the interpretation of hemoglobin A1c levels. However, elevated serum glucose (random), fructosamine, and glycated albumin suggest ongoing hyperglycemia."

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