"Schizophrenia and Diabetes Risk May Share Genetic Link"
November 28, 2015
"A shared gene (or genes) may underlie the co-occurrence of both schizophrenia and type 2 diabetes, according to research published in the FASEB Journal.
It has long been known that schizophrenia is associated with a higher risk of type 2 diabetes, and that mutations in Disrupted in Schizophrenia 1 (DISC1) have been strongly associated with major psychiatric disorders including schizophrenia, but not diabetes.
The new study, conducted by University of Massachusetts researchers Rita Bortell, PhD, and Agata Jurczyk, PhD, is the first to provide a molecular link between type 2 diabetes and psychiatric disorders. It also provides the first evidence indicating that the DISC1 gene plays an unexpected role in pancreatic beta cell function and survival."